When pain doesn't respond to standard care
Chronic pain — particularly nerve-related (neuropathic) pain — can persist despite medication, physical therapy, and other interventions. Conditions sometimes discussed in connection with ketamine include complex regional pain syndrome (CRPS), neuropathic pain, and certain treatment-resistant pain syndromes.
Whether ketamine may be appropriate depends on your diagnosis, history, and overall care plan. A consultation is the place to review this with a medical provider and coordinate with the clinicians already managing your pain.
A different approach to pain signaling
Targets nerve pathways
Ketamine's action on NMDA receptors is thought to influence how chronic pain signals are processed.
Non-opioid
Ketamine works through a different mechanism than opioid pain medications.
Medically supervised
Infusions are delivered in-office with monitoring, following a clinical evaluation.
Ketamine acts on NMDA receptors in the glutamate system, which play a role in how the nervous system processes and amplifies pain. This is a different mechanism from opioids and many common pain medications.
What treatment may involve
Protocols for pain are individualized and may differ from those used for mood conditions. Your provider will discuss what a reasonable plan looks like based on your diagnosis and history, and will coordinate with your existing pain-management team where appropriate.
Ketamine is not a cure for chronic pain, and results vary. It is best considered as one part of a comprehensive, clinician-guided pain-management plan.
Chronic Pain & Ketamine FAQs
Let's talk through your pain history.
Begin with a consultation. We'll review your history, answer your questions, and help you decide if IV ketamine therapy is right for you.
Book a Consultation — reach us your way.
Consultations are scheduled privately by phone and email — no online intake form.
Medical disclaimer. This page is for educational purposes only and does not provide medical advice, diagnosis, or treatment. Ketamine is used off-label for mental health conditions, is not appropriate for everyone, and individual results vary. Candidacy is determined only after a clinical evaluation by a licensed medical provider. If you are in crisis or thinking about harming yourself, call or text 988 or go to the nearest emergency room.